Invasive E. coli infection in infants under three months: A study showing trends in incidence and antibiotic resistance

This article assessed the incidence and antibiotic resistance patterns of infants under the age of three months in the neonatal unit of the level three neonatal unit in Middlesbrough. We provide insights in current trends in the era of established maternal intrapartum Group B Streptococcus prophylaxis and our results can aid optimising local antimicrobial stewardship programmes.

Dr Fabian Johannes Stanislaus van der Velden¹
Specialty Trainee (ST3) in Paediatrics

Dr Sundaram Janakiraman²
Consultant Neonatologist

Dr Igor Kubelka²
Consultant microbiologist

Dr Nataša Ružman²
Consultant microbiologist

Dr Prakash Kannan Loganathan²
Consultant Neonatologist pkannanloganathan@nhs.net

¹Translational and Clinical Research Institute, Newcastle University ²James Cook University Hospital, South Tees Hospitals NHS Foundation Trust

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Keywords

neonatal sepsis; gram-negative sepsis; neonatology; antibiotic resistance; Escherichia coli (E. coli);

Also published in Infant:

VOLUME 16/ISSUE 5, SEPTEMBER 2020

Waving goodbye to the baby train: reducing mother-infant separation and drug errors by collaborative working

This article describes a quality improvement initiative to decrease maternal and newborn separation and to reduce drug errors by stopping the ‘baby train’ of well infants attending the neonatal unit for administration of empirical intravenous antibiotics (IVABs). Utilising bite-sized teaching boxes, midwives were trained to act as a second checker of IVABs alongside a neonatal nurse, keeping mother and babies together on the postnatal ward. The initiative also saw an improvement in patient safety through greater understanding of antibiotic regimen and collaborative working between midwives and neonatal nurses.