Feasibility and efficacy of using volume guarantee with high frequency oscillation for ventilation of preterm infants

This article considers the feasibility of using a newer modality of ventilation for extreme preterm infants to achieve stable carbon dioxide control.

Dr Katarzyna Cooke
Neonatal SPIN Trainee

Dr Amitava Sur
Neonatal Consultant

Dr Anshuman Paria
Neonatal Consultant

Lancashire Women and Newborn Centre, East Lancashire Hospitals NHS Trust amitava.sur@elht.nhs.uk

Cooke K., Sur A., Paria A.Feasibility and efficacy of using volume guarantee with high frequency oscillation for ventilation of preterm infants. Infant 2025; 21(3): 68-69.

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Keywords

high frequency oscillatory ventilation; tidal volume ventilation; bronchopulmonary dysplasia

Key points

High frequency oscillatory ventilation (HFOV) works on the physiological principle of delivering small tidal volumes at supra-physiological frequencies.
Use of volume targeting during HFOV is an attractive newer mode which has been studied in small crossover randomised controlled trials and observational and feasibility studies.
Volume targeting with conventional ventilation has been linked to reduction in incidence of bronchopulmonary dysplasia and intraventricular haemorrhage.

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