Infant Journal
for neonatal and paediatric healthcare professionals

Evidence base for a care bundle to reduce IVH in preterm neonates

Intraventricular haemorrhage (IVH) is a significant complication of premature birth occurring in 20-25% of neonates born before 30 weeks of gestation or with a birth weight of <1,500g. It carries a risk of adverse long-term neurodevelopment outcomes in very low birth weight infants. Multiple strategies are indicated in the literature to reduce the rate of IVH in preterm infants. A systematic literature review was performed and an evidence-based IVH care bundle was developed based on the best available evidence from the literature search.

Aesha Mohammedi
Consultant in Neonatal Medicine

Lawrence Miall
Consultant in Neonatal Medicine

Leeds Teaching Hospitals NHS Trust

Mohammedi A., Miall L. Evidence base for a care bundle to reduce IVH in preterm neonates. Infant 2023; 19(3): 94-99.

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care bundle; intraventricular haemorrhage; extreme preterm babies; very low birth weight; IVH reduction
Key points
  1. 1. There is an ongoing need for a standardised evidence-based IVH care bundle.
  2. A systematic literature review was performed to inform development of an evidence-based IVH care bundle.
  3. A multidisciplinary team approach along with staff education and quality improvement (QI) methodology is needed to implement an IVH care bundle.
  4. A large multicentred research trial incorporating the best evidence-based preventative IVH measures is required.

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