Infant Journal
for neonatal and paediatric healthcare professionals

Establishing a neonatal telemedicine service in Liverpool

Fauzia Paize
Consultant Neonatologist, Liverpool Women’s Hospital

Simon Minford
Advanced Paediatric Nurse Practitioner and Clinical Innovation Consultant, Alder Hey Children’s Hospital

Joanne Minford
Consultant Paediatric and Neonatal Surgeon, Alder Hey Children’s Hospital

Christopher Dewhurst
Consultant Neonatologist, Liverpool Women’s Hospital

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paracetamol; therapeutic drug level; patent ductus arteriosus
Key points
  1. Lower cumulative doses of IV paracetamol may be equally efficacious to higher daily cumulative doses while assuring a better safety profile.
  2. Our review casts doubt on the therapeutic drug concentration of paracetamol as a marker of its safety or efficacy.
  3. Well-designed multicentre RCTs allowing exploration of predictive kinetic behaviour of paracetamol are needed to establish its safety and efficacy over NSAIDs.

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