Infant Journal
for neonatal and paediatric healthcare professionals

Neonatal Research Priority Setting Partnership: help wanted

Katie Evans
Neonatal Research Priority Setting Partnership Project Co-ordinator and Clinical Research Fellow in Neonatal Medicine at Chelsea and Westminster Hospital

Chris Gale
Academic Neonatologist and Neonatal Society Meeting Secretary

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ventilation; pressure-support; preterm ventilation; weaning
Key points
  1. The conventional method to wean ventilation has been to reduce pressure and/or rate on SIMV or switch to SIMV from assist-control ventilation.
  2. PSV is a flow-cycled mode of ventilation that is being used with increasing frequency due to strong physiological rationale.
  3. PSV can be used in isolation or combined with SIMV and VG modes to aid extubation in preterm infants.

Also published in Infant:

Facial paralysis in Haddad syndrome: a case report of Ondine-Hirschsprung’s syndrome with a novel clinical feature
Haddad syndrome is a rare congenital disease that results in an autonomic nervous system dysfunction leading to respiratory failure due to loss of vagal input. In this article we report the case of a newborn male with central hypoventilation syndrome and Hirschsprung’s disease who presented with a facial paralysis – a new clinical presentation in Haddad syndrome. As this disease is not common, we describe the process in which the multidisciplinary team approached the patient and discuss the clinical and genetic aspects, aetiology and treatment.