Neonatal corneal clouding: Manifestation of Peters anomaly
Peters anomaly is a rare congenital condition characterised by central corneal opacification. When there are associated systemic abnormalities, including abnormal ears, cleft lip, cleft palate, short stature and intellectual disability, this is known as Peters plus syndrome. We present a case of Peters plus syndrome diagnosed in infancy after corneal clouding was noted, along with other dysmorphic features, on first newborn examination. We consider the differential diagnosis of similar presentations with corneal clouding, as well as reviewing the potential treatments and prognosis.
Dr Ivory HuangST4 Paediatrics, Queen Elizabeth University Hospital, Glasgow
Dr Carolyne Rennie
Consultant Paediatrician, University Hospital Crosshouse, Kilmarnock
Dr Raju Sunderesan
Consultant Neonatologist, University Hospital Crosshouse, Kilmarnock
raju.sunderesan@aapct.scot.nhs.uk
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- It is important to examine the eyes when a newborn is admitted to NICU.
- Use the mnemonic STUMPED.
- Importance of early recognition, treatment and a multispecialty team approach are crucial for best visual development and to prevent amblyopia.
- Surgery is the only definitive management of Peters anomaly, however, visual prognosis remains guarded.
