Neonatal corneal clouding: Manifestation of Peters anomaly

Peters anomaly is a rare congenital condition characterised by central corneal opacification. When there are associated systemic abnormalities, including abnormal ears, cleft lip, cleft palate, short stature and intellectual disability, this is known as Peters plus syndrome. We present a case of Peters plus syndrome diagnosed in infancy after corneal clouding was noted, along with other dysmorphic features, on first newborn examination. We consider the differential diagnosis of similar presentations with corneal clouding, as well as reviewing the potential treatments and prognosis.

Dr Carolyne Rennie
Consultant Paediatrician
University Hospital Crosshouse, Kilmarnock

Dr Raju Sunderesan
Consultant Neonatologist
University Hospital Crosshouse, Kilmarnock
raju.sunderesan@aapct.scot.nhs.uk