Infant Journal
for neonatal and paediatric healthcare professionals

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procalcitonin; early onset sepsis; sepsis; early onset infection
Key points
  1. Decision making about antibiotic treatment should not rely on any single blood test.
  2. Procalcitonin (PCT) is a potentially useful adjunct to C-reactive protein (CRP) levels in term babies being treated for suspected early onset neonatal infection.
  3. Low PCT and CRP results should allow clinicians to be more confident in their decision to stop antibiotics in apparently well babies. 
  4. PCT results need to be interpreted according to the time they are taken due to physiological variations in PCT after birth.