Infant Journal
for neonatal and paediatric healthcare professionals

Antenatal optimisation for preterm infants less than 34 weeks: a quality improvement toolkit

The British Association of Perinatal Medicine (BAPM) and the National Neonatal Audit Programme (NNAP) are collaborating on four quality improvement toolkits to support perinatal staff to implement the evidence around perinatal optimisation. This article presents the Antenatal Optimisation Toolkit. The evidence for key interventions is described alongside a quality improvement journey, which supports staff to choose improvement solutions most suitable for the local context.

Lauren Shaw
Neonatal Grid Trainee, East Deanery, Scotland

Julie-Clare Becher
Lead for Quality, BAPM and Consultant Neonatologist, Royal Infirmary of Edinburgh,

On behalf of the BAPM Antenatal Optimisation Toolkit Group

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congenital nephrotic syndrome; genetics congenital renal abnormality;
Key points
  1. It is important to further investigate any symptoms that do not fit with an initial diagnosis.
  2. The genetic basis for congenital nephrotic syndrome (CNS) is becoming better defined and testing is more readily available.
  3. The NPHS1 gene encodes nephrin and is implicated in autosomal recessive Finnish-type CNS.
  4. CNS can also be caused by genetic defects in NPHS2, LAMB2 and WT1 genes.