Infant Journal
for neonatal and paediatric healthcare professionals

Hereditary folate malabsorption: effect of systemic folate supplements on myelination

Folate deficiency is a rare but important cause of macrocytic anaemia in infancy. This article describes folate deficiency in a four-month-old male infant who presented with non-specific symptoms, but was found to have megaloblastic anaemia with very low serum folate due to congenital folate malabsorption. The critical role of folic acid in brain development is highlighted.

Siba Prosad Paul, David C.A. Candy, Peter Clayton, W.K. Chong, Ann Wallace