Recent advances in inhaled nitric oxide therapy in neonates: A review of the evidence

Inhaled nitric oxide has been used to treat babies with hypoxaemic respiratory failure for over 15 years and there are now a number of randomised controlled trials that have examined the safety and efficacy of this therapy. This article reviews the evidence base and provides a systematic review and meta-analysis of randomised controlled trials of inhaled nitric oxide in term and preterm babies.

Christopher Dewhurst, Sundeep Harigopal and Nimish Subhedar