The choice of surfactant for treatment of respiratory distress syndrome in preterm infants: A review of the evidence

There are many clinical trials of surfactant therapy in newborn babies, but making valid comparisons between surfactant preparations is problematic due to the different doses, volumes and treatment schedules used. This article reviews the evidence available from clinical trials comparing different surfactant preparations and describes a meta-analysis of three randomised, controlled trials comparing Curosurf and Survanta.