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Volume 15/Issue 4, July 2019

Even less invasive: refinement of the LISA procedure improves success with less sedation

Anne W.Y. Beh, Emily C. Taylor, Peter R. Reynolds


The LISA (less invasive surfactant administration) procedure is established as the preferred method for surfactant administration in the neonatal unit at St Peter’s Hospital. A previous audit published in Infant in 2017 detailed our experience with LISA; since then, we have refined the process and this has led to the use of less sedation, improved success rates and maintained comfort for babies. Rescue surfactant is now being administered at lower oxygen thresholds, in line with the local guideline. In this article we describe the changes made and present the results of a re-audit.

Beh A.W., Taylor E.C., Reynolds P.R. Even less invasive: refinement of the LISA procedure improves success with less sedation. Infant 2019;15(4): 146-48.
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